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May 7, 2012

Scientists 'switch off' brain cell death

Scientists have figured out how to stop brain cell death in mice with brain disease which could provide a deeper understanding of neurodegenerative diseases such as Alzheimer's and Parkinson's.

British researchers writing in the journal Nature say they have found a major pathway leading to brain cell death in mice with prion disease, the mouse equivalent of Creutzfeld-Jacob Disease (CJD).

They then worked out how to block it, and were able to prevent brain cells from dying, helping the mice live longer.

The finding, described by one expert as "a major breakthrough in understanding what kills neurons", points to a common mechanism by which brain diseases such as Alzheimer's, Parkinson's and CJD damage the nerve cells.

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