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February 8, 2011

Math may help calculate way to find new drugs for HIV and other diseases

Math may help calculate way to find new drugs for HIV and other diseases
Using mathematical concepts, Princeton researchers have developed a method of discovering new drugs for a range of diseases by calculating which physical properties of biological molecules may predict their effectiveness as medicines.

The technique already has identified several potential new drugs that were shown to be effective for fighting strains of HIV by researchers at Johns Hopkins University.

"The power of this is that it's a general method," said Princeton chemical and biological engineering professor Christodoulos Floudas, who led the research team. "It has proven successful in finding potential peptides to fight HIV, but it should also be effective in searching for drugs for other diseases."

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