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April 20, 2012

Photoreceptor transplant restores vision in mice

Scientists from the UCL Institute of Ophthalmology have shown for the first time that transplanting light-sensitive photoreceptors into the eyes of visually impaired mice can restore their vision.

The research, published in Nature, suggests that transplanting photoreceptors -- light-sensitive nerve cells that line the back of the eye -- could form the basis of a new treatment to restore sight in people with degenerative eye diseases.

Scientists injected cells from young healthy mice directly into the retinas of adult mice that lacked functional rod-photoreceptors. Loss of photoreceptors is the cause of blindness in many human eye diseases including age-related macular degeneration, retinitis pigmentosa and diabetes-related blindness.

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