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May 7, 2012

Training immune system to fight cancer comes of age

More than 100 years after researchers first explored the potential to harness the body's immune system to fight cancer, the field's leading doctors see the concept finally proving itself on a large scale in the next year or two.

Two drugs based on immunotherapy are already available and have met with mixed results. Bristol-Myers Squibb's Yervoy has been hailed as a major breakthrough for treatment of melanoma since its approval last year, while Dendreon Corp's Provenge prostate cancer vaccine has been hampered by management missteps and doctors' reluctance to adopt the difficult-to-administer therapy after two years on the market.

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