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March 9, 2011

Newly identified spider toxin may help uncover novel ways of treating pain and human diseases

Newly identified spider toxin may help uncover novel ways of treating pain and human diseases
Spider venom toxins are useful tools for exploring how ion channels operate in the body. These channels control the flow of ions across cell membranes, and are key components in a wide variety of biological processes and human diseases.

A newly identified toxin from the American funnel web spider acts on T-type and N-type calcium channels, researchers from the University of California at Riverside have discovered. The toxin offers a new target for studying T-type channels, which play a role in congestive heart failure, hypertension, epilepsy and pain.

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